Why is a thick blood smear considered to have a higher sensitivity than a thin blood smear?

Thick blood film More sensitive by 30 times than thin films because: the blood is concentrated allowing a greater volume of blood to be examined and. malaria parasites are concentrated as the RBCs are lysed.

Why is a thin smear better than a thick smear?

1. Thick blood smears are most useful for detecting the presence of parasites. Thin blood smears helps to discover which species of parasite is causing the infection.

What is the difference between thick and thin blood smear?

Thin and thick smears are two different types of blood smears that contain red blood cells. In a thin smear, a drop of blood is spread across a large area of a slide. In a thick smear, a drop of blood is put on a glass slide.

What is the purpose of thick smear purpose of thin smear?

Thick and thin blood smears will let doctors know the percentage of red blood cells that are infected (parasite density) and what type of parasites are present. A thick blood smear is a drop of blood on a glass slide.

What is the difference between blood film and smear?

Left smear is unstained, right smear is stained with Wright-Giemsa stain. A blood smear, peripheral blood smear or blood film, is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically.

Why are thick or dense smears less likely to provide a good smear preparation for microscopic evaluation?

Why are thick or dense smears less likely to provide a good smear preparation for microscopic evaluation? It will diminish the amount of light that can pass through making it difficult to visualize the morphology of single cells under the microscope. Some times the stain can’t penetrate all of the bacteria.

What is the importance of thick smear for the diagnosis of malarial parasite?

Thick smears consist of a thick layer of dehemoglobinized (lysed) red blood cells (RBCs). The blood elements (including parasites, if any) are more concentrated (app. 30×) than in an equal area of a thin smear. Thus, thick smears allow a more efficient detection of parasites (increased sensitivity).

Why do you have to Dehemoglobinized the thick smear?

Thick blood smears concentrate dehemoglobinized red blood cells to improve parasite detection while thin films are a single layer of red blood cells used to identify the infecting species.

What is the purpose of Giemsa stain?

Giemsa stain is performed on paraffin sections. It is used to stain the blood cells of hematopoietic tissues. It can also be applied to all tissue sections in which the presence of microorganisms is suspected. Gram + and Gram Bacteria are not differentiated with this staining.

What is difference between thick and thin?

As adjectives the difference between thick and thin

is that thick is relatively great in extent from one surface to the opposite in its smallest solid dimension while thin is having little thickness or extent from one surface to its opposite.

What’s the advantage of a blood smear compared to a complete blood count?

What’s the advantage of a blood smear compared to a complete blood count? “Blood smears focus on red blood cells, white blood cells, platelets, and in some cases, they help identify blood parasites. Viruses cannot be identified with this technique due to their small size. What structures does Giemsa stain?

What is blood smear interpretation?

A blood smear is a type of blood test. It looks at the appearance, number, and shape of your red and white blood cells and platelets to see whether they are normal. A blood smear can also detect parasites in your blood. It is now more common to have blood analyzed by a computer.

Why thick smear is not fixed?

Thick smear.

It is not fixed in methanol; this allows the red blood cells to be hemolyzed, and leukocytes and any malaria parasites present will be the only detectable elements.

What is the disadvantage of having a really thick smear when staining?

Do NOT make your smear suspensions too thick. The dye will not penetrate well, and there will be far too many bacterial cells to see individual shapes and arrangements.

What is the effect if the blood of drop is too thick?

Blood that is too thick can lead to blood clots, and blood that is too thin can lead to easy bruising or bleeding. Problems with blood thickness can occur from birth, or develop later in life. Blood thickness may be affected by foods, drugs, and various medical conditions.