What is CSF analysis?

A CSF analysis is a group of tests that look at your cerebrospinal fluid to help diagnose diseases and conditions that affect the brain and spinal cord. Other names: Spinal Fluid Analysis, CSF Analysis.

What is CSF testing?

Cerebrospinal fluid (CSF) analysis is a group of laboratory tests that measure chemicals in the cerebrospinal fluid. CSF is a clear fluid that surrounds and protects the brain and spinal cord. The tests may look for proteins, sugar (glucose), and other substances.

Why we do CSF test?

Why the Test is Performed

CSF analysis can be used to diagnose certain neurologic disorders. These may include infections (such as meningitis) and brain or spinal cord damage. A spinal tap may also be done to establish the diagnosis of normal pressure hydrocephalus or bleeding into the spinal fluid from an aneurysm.

What is the normal amount of CSF?

In normal adults, the CSF volume is mL [1]; approximately 20 percent of the CSF is contained in the ventricles; the rest is contained in the subarachnoid space in the cranium and spinal cord. The normal rate of CSF production is approximately 20 mL per hour.

What can be found in CSF?

The CSF that is collected during a lumbar puncture will contain protein and glucose and may also contain white blood cells. It will be examined to detect any disruption to the normal flow of CSF or damage to the blood-brain barrier.

How do you read CSF results?

Interpretation of CSF results from lumbar puncture (LP)

  1. Appearance: Clear.
  2. Opening pressure: 10-20 cmCSF.
  3. WBC count: 0-5 cells/µL. < 2 polymorphonucleocytes [PMN]) …
  4. Glucose level: >60% of serum glucose.
  5. Protein level: < 45 mg/dL.
  6. Consider additional tests: CSF culture, others depending on clinical findings.

Where is CSF tested?

A lumbar puncture (spinal tap) is performed in your lower back, in the lumbar region. During a lumbar puncture, a needle is inserted between two lumbar bones (vertebrae) to remove a sample of cerebrospinal fluid. This is the fluid that surrounds your brain and spinal cord to protect them from injury.

Is CSF test painful?

During the procedure: You will lie on your side or sit on an exam table. A health care provider will clean your back and inject an anesthetic into your skin, so you won’t feel pain during the procedure.

What is CSF leak symptoms?

Cranial CSF leaks

Clear, watery drainage from the nose or ear (on one side) Hearing loss. A metallic taste in the mouth. Meningitis.

How much does a CSF test cost?

Cerebral Spinal Fluid (CSF) Test Cost

City Average Price Price Upto
Mumbai Rs. 788.00 Rs. 1500.00
Nalgonda Rs. 440.00 Rs. 600.00
Delhi Rs. 584.00 Rs. 1500.00
Noida Rs. 459.00 Rs. 650.00

What color is CSF?

Color of the fluid—normal is clear and colorless. Changes in the color of the CSF are not diagnostic but may point to additional substances in the fluid. Yellow, orange, or pink CSF may indicate the breakdown of blood cells due to bleeding into the CSF or the presence of bilirubin.

What type of fluid is CSF?

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations.

Why is CSF colorless?

The fluid that is obtained from a spinal tap is called cerebrospinal fluid or CSF, for short. Normal CSF is a clear, colorless fluid that contains small quantities of glucose (a sugar) and protein.

What is CSF RBC count?

A CSF cell count is a test to measure the number of red and white blood cells that are in cerebrospinal fluid (CSF). CSF is a clear fluid that is in the space around the spinal cord and brain.

What does WBC in CSF mean?

Cell counts: Red blood cells (RBCs) in the CSF mean bleeding. High levels of white blood cells (WBCs) mean meningitis. Tumor cells and abnormal levels of white blood cells mean cancer. Other Results: Antibodies, bacteria, or other organisms in the CSF mean that an infection or disease is present.

What causes high WBC in CSF?

An increase of white blood cells indicates infection, inflammation, or bleeding into the cerebrospinal fluid. Some causes include: Abscess. Encephalitis.

What causes high glucose in CSF?

Chemical meningitis, inflammatory conditions, subarachnoid hemorrhage, and hypoglycemia also cause hypoglycorrhachia (low glucose level in CSF). Elevated levels of glucose in the blood is the only cause of having an elevated CSF glucose level.

What does glucose in CSF indicate?

A CSF glucose test checks the amount of sugar (glucose) in your cerebrospinal fluid (CSF), a clear liquid that surrounds the spinal cord and brain. The test can detect infections of the brain or spinal cord.

Does CSF test positive for glucose?

No true normal range for glucose in the CSF exists. Your doctor must compare it to the level of glucose in a sample of blood taken within two to four hours of the lumbar puncture. In healthy adults, the ratio of glucose in CSF should be roughly two-thirds of the amount of glucose found in the blood sample.