What does transitional epithelial cells in urine mean?

An epithelial cells in urine test looks at urine under a microscope to see if the number of your epithelial cells is in the normal range. It’s normal to have a small amount of epithelial cells in your urine. A large amount may indicate an infection, kidney disease, or other serious medical condition.

What causes transitional epithelial cells in urine?

A raised amount of epithelial cells in the urine are often the sign of a minor infection, such as a UTI or yeast infection. Anyone with bothersome urinary symptoms should see a doctor for urinalysis and a proper diagnosis.

What does it mean if epithelial cells are transitional?

Transitional epithelium also known as urothelium is a type of stratified epithelium. Transitional epithelium is a type of tissue that changes shape in response to stretching (stretchable epithelium). The transitional epithelium usually appears cuboidal when relaxed and squamous when stretched.

What happens if epithelial cells are present in urine?

A small number of epithelial cells in your urine is normal. A large number may be a sign of infection, kidney disease, or another serious medical condition. For that reason, your doctor may order a urine test or urinalysis to view your urine under a microscope.

What do transitional cells in urine mean?

Transitional cells are able to change shape and stretch. They make up the lining of the renal pelvis, ureters, bladder and urethra. The lining of these organs need cells that can stretch to expand when urine is stored in or flows through them. TCC of the kidney starts in the part of the kidney called the renal pelvis.

Are transitional cells in urine normal?

A few transitional cells are present in the urine of healthy persons. Increased num- bers are associated with infection. Large clumps or sheets of these cells may be seen with transitional cell carcinoma. Most often, urothelial cells are seen after urethral or ureteral catheterization.

Why is transitional epithelial tissue important?

Transitional epithelium: A transitional epithelium (also known as urothelium) is made up of several layers of cells that become flattened when stretched. It lines most of your urinary tract and allows your bladder to expand.

What is unique about transitional epithelium How is this beneficial?

What is unique about transitional epithelium? How is this beneficial? it stretches and then goes back to it’s original shape. It allows for the stretching of the bladder.

How serious is transitional cell carcinoma?

Transitional Cell Carcinoma: An Aggressive Cancer

Transitional cell carcinoma affects the transitional cells of the urinary system and accounts for an overwhelming majority of bladder cancer diagnoses. This cancer may spread rapidly, affecting other organs and becoming life-threatening in some cases.

Is transitional cell carcinoma malignant?

Transitional cell cancer of the renal pelvis and ureter is a disease in which malignant (cancer) cells form in the renal pelvis and ureter. The renal pelvis is the top part of the ureter. The ureter is a long tube that connects the kidney to the bladder.

How long do you live with transitional cell carcinoma?

The median overall survival (OS) was 46 months, and the 5-year OS rate was 41.8%. The median cancer-specific survival (CSS) was 78 months, and the 5-year CSS rate was 54.3%.

Can transitional cell carcinoma be cured?

Current treatments for transitional cell carcinoma include: Endoscopic resection, fulguration, or laser surgery. Through a ureteroscope, physicians can destroy or remove cancer cells with direct tumor removal, electrical current, or laser.

How rare is TCC of the kidney?

Over 80,000 cases of bladder cancer are diagnosed annually in the United States. Upper urinary tract TCC is estimated to occur in 5% of all urothelial cancers and in fewer than 10% of renal tumors.

Where does transitional cell carcinoma metastasis?

Transitional cell carcinoma (TCC) of the bladder typically metastasizes to the pelvic lymph nodes and to visceral sites including the lungs, liver, and bones. Other sites include the brain, especially after systemic chemotherapy.