How is newborn surfactant given?

Surfactant has been administered either by disconnecting the infant from the ventilator and applying bagging, or by continuing ventilation during the procedure.

How is surfactant administered to newborns?

The surfactant is administered via a thin catheter into the trachea in small aliquots, while the baby is spontaneously breathing on CPAP support. In infants 29-32 weeks gestation, LISA may reduce the occurrence of pneumothorax and need for mechanical ventilation.

When do you give neonatal surfactant?

Ideally the dose should be given within 1 hr of birth but definitely before 2 hours of age. A repeat dose should be given within 4 – 12 hours if the patient is still intubated and requiring more than 30 to 40% oxygen.

How long after birth can you give surfactant?

Optimal timeframe for surfactant administration: a. The optimal time for rescue surfactant administration is within 2 to 6 hours of birth. b. In general, the literature does not support giving a first dose of surfactant past about 24 hours of life.

When do you give surfactant therapy?

Surfactant replacement therapy should be considered in:

  1. neonates with clinical and radiographic evidence of RDS.
  2. neonates at risk of developing RDS (e.g. <32 weeks or low birth weight <1300g)
  3. neonates who are intubated, regardless of gestation, and requiring FiO2 >40%

How do you administer surfactant?

Surfactant has been administered either by disconnecting the infant from the ventilator and applying bagging, or by continuing ventilation during the procedure.

How do you inject SURVANTA?


  1. Instill through 5 French endhole catheter inserted into endotracheal tube just above carina (not into bronchus)
  2. Inject each dose into catheter over 2-3 seconds.

How long does it take surfactant to work?

Many babies start to get better within 3 to 4 days, as their lungs start to make surfactant on their own. They’ll start to breathe easier, look comfortable, need less oxygen, and can be weaned from the support of CPAP or a ventilator.

How many doses of surfactant can you give?

WHAT DOSAGE SHOULD BE USED? Dosages have varied from 25 mg to 200 mg phospholipids/kg body weight as single doses in the different clinical trials. Studies of different dosing regimens are limited. Surfactant-TA (a natural bovine surfactant) was more effective at a dose of 120 mg/kg than 60 mg/kg (54).

How do you give surfactant video?

And now administering the surfactant depress the syringe administering the surfactant add a around you want to take around 15 to 30 seconds.

What is newborn surfactant?

Surfactant is a liquid made by the lungs that keeps the airways (alveoli) open. This liquid makes it possible for babies to breathe in air after delivery. An unborn baby starts to make surfactant at about 26 weeks of pregnancy.

How do you give curosurf?

Quote from Youtube:
But do not shake initial doses of curosurf are administered at a volume of 2.5 milliliters per kilogram or 200 milligrams per kilogram.

When do you administer CUROSURF?

The initial recommended dose of CUROSURF is 2.5 mL/kg birth weight. Up to 2 repeat doses of 1.25 mL/kg birth weight each may be administered at approximately 12‑hour intervals. A total of 4 doses of Survanta (4 mL/kg birth weight) can be administered no more frequently than every 6 hours in the first 48 hours of life.

When can you suction after surfactant?

7.5 Tracheal suctioning should be avoided immediately following surfactant administration if ventilation can be adequately maintained. Most studies suggest a time period of 1–6 hours following surfactant delivery.

Why do premature babies need surfactant?

Surfactant replacement therapy for premature babies acts to keep the alveoli from sticking together, and is supplemented with oxygen or ventilation to help the baby breathe. The majority of premature babies recover from RDS without major complications, while others are at risk for chronic breathing difficulties.

What is the Lisa method?

Less invasive surfactant administration (LISA) uses a thin catheter inserted into the trachea to deliver the surfactant. During the procedure, the infant is breathing spontaneously while supported with continuous positive airway pressure.

How is surfactant produced?

Surfactant is made by the cells in the airways and consists of phospholipids and protein. It begins to be produced in the fetus at about 24 to 28 weeks of pregnancy, and is found in amniotic fluid between 28 and 32 weeks. By about 35 weeks gestation, most babies have developed adequate amounts of surfactant.

Is surfactant a medication?

Pulmonary surfactant is used as a medication to treat and prevent respiratory distress syndrome in newborn babies. Prevention is generally done in babies born at a gestational age of less than 32 weeks. It is given by the endotracheal tube. Onset of effects is rapid.

Can you give surfactant to adults?

Administration of exogenous pulmonary surfactant is an adjunctive therapy that may help adult patients with ARDS. Pulmonary surfactant is produced by type II alveolar cells and is composed of two major fractions: phospholipids (90%) and surfactant-specific proteins (10%).

What is surfactant injection?

Surfactant is a liquid made by the lungs that keeps the airways (alveoli) open. Surfact 108mg Injection provides lubrication and helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out of the lungs of the baby.